Jessica Frakes, MD

Radiation Liaison

Dr. Jessica Frakes is an Assistant Member in the Department of Radiation Oncology at Moffitt Cancer Center. She received her MD from the University of South Florida Morsani College of Medicine. Dr. Frakes recently completed her Radiation Oncology Residency at the University of South Florida / Moffitt Cancer Center. Her clinical expertise is the use of radiation therapy to help patients diagnosed with gastrointestinal cancers, including esophageal, gastric, pancreatic, hepatobiliary, rectal and anal cancer. Dr. Frakes is experienced in the personalized use of advanced radiation techniques that include stereotactic body radiation therapy (SBRT), intensity modulated radiation therapy (IMRT), image-guided radiation therapy (IGRT), and liver-directed therapies such as radiation embolization. Her research interest includes improving outcomes and decreasing toxicity for the treatment of gastrointestinal cancers, with a strong focus on esophageal cancer. Dr. Frakes is a key member of the esophageal cancer research team, and she is dedicated to the advancement of multimodality treatments and the expansion of clinical trials.

Education & Training


  • University of South Florida Moffitt Cancer Center – Radiation Oncology

Medical School:

  • University of South Florida Morasani School of Medicine – MD

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